Infertility immunology and
lipid infusion therapy
What is infertility?
The concept of infertility is essentially covers the inability to procreate. According to medical terminology, a couple is considered infertile if they fail to conceive for six months to a year (depending on age) without regular unprotected sex.
Infertility (infertility) can affect both women and men, and for various reasons. These may be genetic factors, lifestyle factors, diseases or psychosomatic factors. Coping with infertility is a serious emotional and mental challenge for couples.
Because of the seriousness of the problem, it is important to understand the possible causes of infertility.
Finding the causes of infertility
When examining the background to infertility, it is important to a thorough health check for both members of the couple.
In women, the most common causes of infertility include a gynaecological problem (e.g. endometriosis, blockage of the fallopian tubes), a hormonal disorder or an immune system disorder. In many cases, it can be a combination of several different conditions.
The most common causes of male infertility are low sperm count or poor sperm motility. Genetic factors may also play a role.
What is infertility immunology?
Immunology, the science of how the immune system works, has become increasingly important in recent decades in the investigation and treatment of the causes of infertility.
The relationship between infertility and immunology is based on the thesis that immune system disorders can contribute to infertility. The immune system not only plays a role in defending against infections and diseases, but is also key to reproductive processes.
During the immune system, different cells coordinate the body's defence mechanisms. Normally, the immune system recognises and destroys harmful pathogens, but sometimes the system can malfunction and the body turns against its own cells.
This autoimmune reaction can lead to infertility and recurrent miscarriages.
Prevalence of vaccinations and the immune response
The relationship between miscarriage rate and immune function is a particularly important area of research in infertility immunology. Several studies have shown that immune dysfunction is associated with early miscarriages. If the fetus passes several times in early pregnancy, but there are no hormonal or organ problems, it is likely to be due to an immunological disorder.
When examining the immune system, it is important to know that both innate and acquired immunity can be disturbed. In both cases, the body turns on itself and attacks the embryo as a hostile entity.
The following immune disorders may be associated with infertility immunology:
- Systemic immune diseases - Autoimmune diseases in which the immune system attacks not a single organ but several organ systems or the whole body, such as systemic lupus erythematosus (SLE).
- Alloimmunity disorder - An immune response in which the body rejects the foetus or already prevents it from attaching.
- Organ-specific immune diseases - Autoimmune diseases are diseases in which the immune system specifically attacks the cells of a particular organ, which may be the ovaries. As a consequence, the possibility of getting pregnant is greatly reduced.
How are miscarriage and immune response linked?
To understand the link between miscarriage and the immune response, it is important to consider that during pregnancy, the embryo is semi-open to the female body, as it also contains the paternal gene pool. Normally, the immune system recognises this semi-foreign tissue and develops a tolerance to it, allowing the pregnancy to develop without disturbance.
However in some cases, the immune system cannot properly recognise and tolerate the embryo, which can lead to autoimmune reactions. This is particularly common in women who suffer from autoimmune diseases such as lupus or thyroid disorders.
Research into the link between miscarriages and the immune response has discovered that the presence of certain antibodies can also increase the risk of miscarriage. Antiphospholipid antibody syndrome (APS), for example, is a condition in which the body produces antiphospholipid antibodies that can interfere with blood clotting and placental function, causing miscarriage.
The role of diagnosis
Diagnosing immunological problems in infertility is a complex process that involves involves a number of tests and examinations.
For couples blood tests measure the presence of antibodies that may attack the embryo or sperm. Also hormonal tests and genetic tests may also be needed to get a full picture of the immune system and its impact on reproductive health.
Dr. Angéla Fülöp, immunologist and rheumatologist, is available at
lipid infusion therapy
Dr. Angéla Fülöp immunologist, to detect and treat immune-derived lesions. He does this with great expertise and decades of experience.
Lipid infusion for infertility treatment is available on prescription.
Find out more about the Doctor and make an appointment!
How to tackle the problem of infertility immunology?
The treatment of immunological problems in infertility requires a complex and personalised approach. One of the most effective treatment methods is lipid infusion therapy, which has become increasingly popular in recent years.
What is a lipid infusion?
Lipid infusion treatment involves the intravenous administration of lipids (fatty acids), vitamins and trace elements, among other things, which help regulate the immune system. This treatment can be particularly useful for women whose immune system is overactive and attacks the embryo, preventing successful implantation and pregnancy.
The effectiveness of lipid infusions lies in their ability to help reduce inflammation and promote embryo implantation in the uterine lining. They also support cell-to-cell communication and improve blood flow to the reproductive organs, further increasing the chances of a successful pregnancy.
Lipid infusion therapy is safe and has minimal side effects. It aims to maximise the chances of a successful pregnancy. The treatment protocol is personalised and based on individual needs and medical findings.
Immunology in the BMM
The immune system is extremely complex. Immunology is concerned with the detection of its disorders. The immune system's primary role is to protect the body against pathogens, ensuring that the body stays healthy.
During immunological examinations, doctors carry out various tests to identify possible disorders of the immune system.
These tests may include blood tests, detection of the presence of autoantibodies and assessment of specific immune responses. Immunological tests are designed to detect if the immune system is malfunctioning, for example, if it is attacking your own body's cells or if it is not responding properly to external pathogens.
With this information, the specialist immunologist will develop a targeted treatment plan to restore optimal immune function.
In the case of infertility, immunological tests can help to understand how a malfunctioning immune system may be contributing to difficulties in conception. Based on this information, appropriate treatment, such as lipid infusions, can increase the chances of getting pregnant. This can also Dr. Angéla Fülöp, immunologist, can help.
Our specialist immunologist
Dr. Angéla Fülöp
Immunologist and rheumatologist